The article describes modern methods of diagnosis and treatment of Mirizzi Syndrome. Despite a wide range of surgical methods for treating this syndrome, the results of treatment to date remain not entirely satisfactory. The presence of Mirizzi Syndrome in a patient during surgery increases the risk of intra- and postoperative complications. Difficulties in diagnosing Mirizzi syndrome, the risk of damage to the bile duct, several observations, as well as a fairly wide range of surgical treatment methods determine the relevance of studying this problem. The introduction of modern methods for diagnosing MS and the development of rational surgical tactics, depending on the type of syndrome, will make it possible to improve the treatment of patients with this complication of gallstone disease.