Volume - 13 | Issue-1
Volume - 13 | Issue-1
Volume - 13 | Issue-1
Volume - 13 | Issue-1
Volume - 13 | Issue-1
Objective: In different investigations, phytoconstituents of star anise have demonstrated outstanding antiviral activity against diverse viral species. Consequently, the study's goal was to use in-silico methodologies to assess the effectiveness of star anise phytoconstituents against the Marburg virus protein. Method : Auto Dock was employed to test chosen star anise phytochemical molecules on Marburg virus protein, and Discovery Studio visualizer was used to make 3D and 2D interface images. Result : Blind docking all eight phytochemicals revealed that two of the eight phytochemicals created conventional carbon-hydrogen bonds, and that eugenol and Farnesol both formed carbon-hydrogen bonds. The lowest binding energy was determined to be -6.00 kcal/mol for beta -eudesmol. Conclusion : Based on the substantial binding energies of phytoconstituents during blind docking, our findings revealed that star anise phytoconstituents can have a beneficial effect against Marburg virus. Beta eudesmol might be a viable alternative to Marburg virus.