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ISSN 2063-5346
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BIOCHEMISTRY OF FASTING – A REVIEW ON METABOLIC SWITCH AND AUTOPHAGY.
Volume - 13 | Issue-1
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ONE-POT ENVIRONMENT FRIENDLY SYNTHESIS OF IMINE DERIVATIVE OF FURFURAL AND ASSESSMENT OF ITS ANTIOXIDANT AND ANTIBACTERIAL POTENTIAL
Volume - 13 | Issue-1
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MODELING AND ANALYSIS OF MEDIA INFLUENCE OF INFORMATION DIFFUSION ON THE SPREAD OF CORONA VIRUS PANDEMIC DISEASE (COVID-19)
Volume - 13 | Issue-1
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INCIDENCE OF HISTOPATHOLOGICAL FINDINGS IN APPENDECTOMY SPECIMENS IN A TERTIARY CARE HOSPITAL IN TWO-YEAR TIME
Volume - 13 | Issue-1
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SEVERITY OF URINARY TRACT INFECTION SYMPTOMS AND THE ANTIBIOTIC RESISTANCE IN A TERTIARY CARE CENTRE IN PAKISTAN
Volume - 13 | Issue-1
MOLECULAR DOCKING STUDIES OF 2-AMINO-4,6- DISUBSTITUTED PYRIDINE-3-CARBONITRILES AGAINST ADENOSINE A2A RECEPTOR AS POTENTIAL ANTI PARKINSONIAN AGENTS.
Main Article Content
Abstract
Introduction: Parkinson’s disease has become one of the most concerned diseases in the recent days. All the Adenosine A2A receptor antagonists were known to exhibit Antiparkinsonian activity. In the present study various 2-Amino-4,6-Disubstituted Pyridine-3-Carbonitriles or 2-amino 3-cyano pyridines were designed and docked against Adenosine A2A receptor for Antiparkinsonian activity. The ligands were compared with that of the standard Adenosine A2A receptor antagonists like Istradefylline and Caffeine.
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