This review article provides an overview of the pharmacological and plant chemistry of the alba species of Morus. Morus alba (mulberry) is a medicinal plant which belongs to family Moraceae. It has been used as a medicine since ages due to its various therapeutic properties. Various mulberry plant components have been shown to have hepatoprotective, anti-oxidant, cardiovascular, anti-obesity, anti-inflammatory, anti-cancer, anti-microbial, anti-mutagenic, anti-diabetic and nephroprotective properties. Other medicinal effects of mulberry include anti-platelet, anti-depressant, anti-asthmatic, immune modulatory, gastrointestinal and cholesterol lowering effects. The plant contains various phytochemicals such as flavonoids, alkaloids, anthocyanins, tannins, glycosides, terpenoids, steroids, phytosterols, saponins, benzofuran derivatives. This phytopharmacological study indicates that Morus alba can be used as a of therapeutic in future use.