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ISSN 2063-5346
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MOUTH DISSOLVING FILMS: A NOVEL CONVENIENT DOSAGE FORM FOR RAPID RELIEF

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Diwas Adhikari, Meenakshi Kandwal, Dr. Shivanand Patil
» doi: 10.48047/ecb/2023.12.si4.1599

Abstract

With advancement in the therapeutic evolution, novel drug delivery has been started appearing growing immediately into the new dosage forms called as Mouth Dissolving films, also known as Orally Disintegrating films. They are specially designed for dissolving locally inside the mouth, do not require water for disintegration and exerts its therapeutic effect immediately due to easy accessibility to oral mucosa. It also leads to the higher bioavailability as the first pass metabolism is bypassed. Pediatric, Geriatric and Dysphagic patients are highly benefitted through these dosage forms who have difficulty in swallowing thus promoting a patient compliance. These Dosage forms can be specially developed using Solvent Casting Method. Apart from these other methods are also used like Hot Melt Extrusion Method, Rolling Method, Semisolid casting method, Solid dispersion extrusion methods etc. Materials such as Active Pharmaceuticals Ingredients, Saliva Stimulating agents, Plasticizer, Surfactants, Artificial Sweeteners, Film forming Polymers, Superdisintegrants and desired solvent can be employed for the preparation. Prepared films can be evaluated for various attributes like Folding Endurance, Content Uniformity, Disintegration time, Assay %, Tack Test, Tensile Strength, Surface pH, Percentage elongation, Swelling Properties, Dissolution test, Moisture Absorption, Moisture Loss etc. This article provides an overview regarding Mouth dissolving films, its preparation and Evaluation. Novel technologies developing the mouth dissolving films of the different therapeutic category have been a part of the research of many pharmaceuticals researchers. Technological and economical investment of the global authorities is required for enhancing this technological boon as an alternative approach among others conventional dosage forms.

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