Objectives: To compare the effect of myofascial release technique versus proprioceptive neuromuscular facilitation on cervical Pain, disability, pain pressure threshold and range of motion in chronic mechanical neck pain patients. Methods: 60 chronic mechanical neck pain right handed patients were involved in this randomized controlled trial. They were recruited from El-Hosary family health center and randomly assigned into three groups. All groups received conventional treatment of mechanical neck pain, while group A received myofascial release in addition and group B received proprioceptive neuromuscular facilitation in addition. Pain, disability, pain pressure threshold and range of motion were measured at baseline, after six sessions, after 12 sessions and at 3months follow up.