Patients with advanced chronic kidney disease (CKD) experience many bothersome symptoms, affecting their quality of life (QOL). The majority of these patients do not have the opportunity to receive a kidney transplant and need other treatments for these burdensome symptoms in order to improve their QOL and prognosis. With growing attention to the significance of symptom management in advanced CKD on haemodialysis, the evidence regarding symptoms is increasing. In this review, we briefly summarize the current evidence of only non-pharmacologic interventions to improve symptoms and QOL in patients with advanced CKD, on dialysis. We focused on symptoms that are commonly experienced by patients, such as pain, fatigue, sleep disturbances, itching, nausea and vomiting, cognitive impairment, and anxiety and depression