This paper focuses on numerical modeling of cannabis extraction in supercritical fluid extraction (SFE) CO2 process. First, two mathematical models, Sovova and Reverchon, are described. COMSOL program was used to solve numerical solution of both models. Then, verification of numerical models is shown. The extraction experiment was set up. Cannabis Savita L. oil was extracted in SFE CO2 process. Extraction pressure and temperature conditions were 200 bars and 50oC, respectively. Numerical model was customized for Cannabis Savita L. To improve solution accuracy, total mass transfer was fitted from experimental data. RMS was used to optimize total mass transfer coefficient. Experimental results and the proposed numerical solutions were in a good agreement