Background: Obstetrics and Gynecology (O&G) surgery is essential in treating obstetrical and gynecological conditions, but it can cause physical and psychological distress to patients. Evidence-based nursing (EBN) offers a valuable approach to addressing patients' emotional needs and enhancing surgical outcomes. Despite advancements in nursing care, there is limited research on the application of EBN in the O&G operating room. Objective: This review aims to examine the roles of nurses in O&G operating rooms, evaluate their training needs, assess challenges they face, explore the impact of teamwork on patient outcomes, and identify best practices for nursing care improvement in this specialized setting. Conclusion: Obstetric nurses play a critical role in the O&G operating room, providing comprehensive care to pregnant women before, during, and after surgical procedures. They face challenges such as high-pressure environments, staffing shortages, and complex team dynamics. The establishment of a nursing platform integrating electronic medical records and sensor technology is proposed to enhance patient care and nursing management. By emphasizing evidence-based nursing practices, this research aims to enhance the quality of care in O&G operating rooms and improve patient outcomes.