The optimal characterization of carrot juice powder was designed in a central composite design model to analyze different spray dryer parameters such as inlet airflow temperature (155℃– 175℃), the addition of maltodextrin for acquiring proper encapsulation (5% - 15%), and feed rate (400 ml/h – 600 ml/h). The experimental results were (P < 0.05) fitted in quadratic polynomial order to analyze the various responses as powder yield (%), hygroscopicity (g/100g), total anthocyanin content (%), and RSA value (%). Powder yield increased with an increase in inlet air temperature, but anthocyanin content and color retention decreased.