Percutaneous nephrolithotomy (PCNL) is today the gold standard for the management of patients with renal calculi as it is less invasive than the open surgery, less time consuming, and is associated with less chances of infection. It is also associated with lower morbidity and faster recovery. However, placement of nephrostomy tube results in distressing peritubal pain requiring administration of analgesia. Inadequate analgesia can result in delayed mobilization, impaired ventilation, and prolonged hospitalization, which increases cost and causes delay of patient recovery and return to daily activities.. In addition, poor postoperative pain control contributes to patient dissatisfaction with the surgical experience and may have adverse psychological consequences. Tubeless PCNL can avert this problem but can be performed only in the selected patients. Analgesics such as non-steroidal anti-inflammatory drugs and opioids have side effects that limiting their use in patients with potential renal problems. There are multiple methods to diminish the intensity of postoperative pain. It may be lowered after tubeless and totally tubeless procedures or applying a small bore nephrostomy tube. The transversus abdominis plane (TAP) block is a peripheral nerve block which anaesthetises the abdominal wall. The increasing use of TAP block, as a form of pain relief after abdominal surgery warrants evaluation of its effectiveness as an adjunctive technique compared with other analgesic techniques. The aim of this study was to review the effective role of oblique subcostal TAP block for percutaneous nephrolithotomy