Materials used for fixed partial denture (FPD) frameworks have had properties of excellent strength,durability, and biocompatibility.Several materials have been used for fabrication of fixed partial denture such as alloys,ceramics, and high‑performance polymers. All these,though excellent, have their advantages and disadvantages.PEEK is a high impact polymer material that is made from fluorine benzene ketone, hydroquinone, and sodium carbonate or potassium carbonate, dissolved in diphenyl sulfone.PEEK can be blended with glass fibers or carbon fibers in order to enhance its mechanical strength. PEEK exhibits superior biocompatibility. It is non-mutagenic and nontoxic to human gingival fibroblasts and osteoblasts. Due to excellent properties of PEEK, it was used as framework for fixed partial prosthesis replacing posterior teeth. This case report describes the technique and fabrication of PEEK framework for FPD.