Lack of knowledge regarding polycystic ovarian syndrome and poor lifestyle choices are considered to be the major factor leading to polycystic ovarian syndrome. Aim: The study aimed to evaluate perception of the female university students toward polycystic ovarian syndrome Design: A Quasi-experimental research design was utilized. Setting: This study was conducted at faculty of Engineering-Fayoum University. Sample: A Convenient sample include 100 female university students Tools: A structured interviewing questionnaire and female university students assessment sheet toward knowledge and attitude regarding polycystic ovarian syndrome Results: the majority of studied female university students had satisfactory level of total knowledge regarding polycystic ovarian syndrome after educational session with a highly statistical significant difference pre\post educational session implementation and more than half of the studied female university students had a negative attitude before educational session. Conclusion: there was highly statistically significant with positive correlation between total knowledge and total attitude scores pre/post educational session implementation and follow up. Recommendation: Implementing an educational program about risk factors and preventive measures of polycystic ovarian syndrome among female university students