Medication safety is a critical aspect of healthcare, particularly in pediatric patients who are more vulnerable to medication errors and adverse drug reactions. Pharmacists play a crucial role in promoting medication safety in this population through various interventions and initiatives. This review article aims to explore the important role of pharmacists in ensuring the safe use of medications in pediatric patients. The article will discuss the different strategies employed by pharmacists to enhance medication safety, such as medication reconciliation, patient counseling, medication therapy management, and collaboration with healthcare teams. Additionally, the review will highlight the challenges faced by pharmacists in promoting medication safety in pediatric patients and propose potential solutions to overcome these challenges. Overall, this review underscores the significance of pharmacists' involvement in safeguarding the health and well-being of pediatric patients through their expertise in medication management and safety.