Medicinal plants have bioactive compounds which are used for curing of various human diseases and also play an important role in healing. Secondary constituents contain alkaloids, flavonoids, phenol, saponins, steroids and tannins. Medicinal plants have anticancer, antimicrobial, antidiabetic, antidiuretic and anti- inflammation activities etc. The increasing interest in powerful biological activity of secondary metabolites outlined the necessity of determining their contents in medicinal plants. Jeera, commonly known as cumin is a popular herbal plant in traditional ayurvedic medicine. The dried seeds of C. cyminum have been traditionally used as food and medicine. The objective of this study was to investigate pharmacognostical, phytochemical features antioxidant and antimicrobial activity of methanolic extracts of C. cyminum seeds