The current study has been done on oldenlandia corymbose, reflect that their botanical name oldenlandia corymbosa linn, common name khet papra, white diamond flower, synonyms hedyotis corymbosa linn., oldenlandia scabrida dc. It is an annual slender herbaceous weed upto 50 cm tall. its show various pharmacological activity hepatoprotective activity, anti-malarial activity, antioxidant activity, anti-bacterial activity, anti-malarial activity, anthelmentic activity, abortifacient activity, anti-diabetic activity, hepatoprotective activity, anticancer activity, antipyretic activity, antioxidant activity, antifungal activity, the object of the study is to choose plants from conventional medical systems and look into their pharmacological profiles related to Type 2 Diabetes & Alzheimer’s Disease. After collection and authentication we done proximate analysis of the plant drug, which included total ash value, loss of drying, foaming index, total tannin content. Extraction is done using soxhlet apparatus using ethanol as a solvent in last we performed pharmacological activity like Cholinesterase enzyme inhibitory activity, Glucosidase enzyme inhibitory activity, Scavengers of nitric oxide, Reducing Power Assay of O. corymbose, The UV-Vis spectra of the 70% ethanol extract of leaf of OC had absorption maxima at 241.6 nm, within the range of characteristic absorption for flavonoids.