Pharmacokinetic monitoring of contrast agents in radiology plays a crucial role in ensuring patient safety and optimal imaging outcomes. This review article explores the significance of pharmacokinetics in radiology, focusing on the nursing implications of contrast agent administration. The article discusses the principles of pharmacokinetics, including absorption, distribution, metabolism, and excretion of contrast agents, and their impact on imaging procedures. Nursing responsibilities in contrast agent administration, monitoring, and management of adverse reactions are highlighted. The review also addresses the importance of patient assessment, education, and communication in ensuring safe and effective contrast agent use. Furthermore, the article examines current practices and challenges in pharmacokinetic monitoring of contrast agents in radiology and discusses potential future directions for research and clinical practice. Overall, this review provides valuable insights for nurses and healthcare providers involved in radiology procedures to enhance patient care and safety.