The evidence supports the beneficial effects of physical activity on focusing and sustained attention, concentration, learning activities, cognitive performance, and memory, and suggests that the effects could be especially significant in children to perform better in their academic success. However, limited research has explored in regard to physical activity as a way to manage behavioral symptoms and improve cognitive-related performance among children with learning-related disabilities including attention deficit hyperactivity disorder (ADHD). Objective: The purpose of this systematic review article is to review the literature concerning the potential of physical activity for the management of symptoms of learning disabilities, ADHD, and other child-related behavioral issues. Methods: An extensive search was conducted through major databases for studies published between 1990 and January 31, 2023, in Google scholar, Scopus, Web of Science core collection, PubMed, PsycINFO, Embase, ISI, and the Cochrane Library, based on the selection criteria. Results: The results revealed that the outcomes of various interventional activities related to physical activity are discussed in detail. Thirteen articles were included in the final review. Due to the variety of methodological approaches, sample size, test estimate, and most critically, the intervention duration, the framework of physical activities, and tests used to measure symptoms, it is troublesome to recognize the best approach of physical activity to intervene in symptoms related to learning related disorders and ADHD. However, it is plausible to argue that physical activity interventions can provide an alternative, non-pharmaceutical approach to the management of learning disorders, especially conduct disorders and ADHD in children. Conclusion: Integrated approach with yoga interventions, mindfulness-based meditation, and aerobic exercises are promising interventional tools for enhancing the motor, attention, imitation skills, and cognitive-related symptoms of children with learning-related disorders