The present study aims to explore the phytochemical and physicochemical analysis of a Siddha classic polyherbal formulation -Thaleesadi Chooranam (T.S.C.). This Thaleesadi Chooranam contains the ingredients like Thaleesadi, black pepper and ginger. Its counterpart keeps the immune system and overall health and well-being. This study aims to estimate the quality of Thaleesadi Chooranam by conducting preliminary phytochemical analysis, with the help of following tests done with H.P.T.L.C. and U.V. -Vis spectrometric analysis, also to know physiochemical parameters like ash value, extractive value and loss on drying as per pharmacopoeial laboratory for Indian medicine guidelines. The T.S.C., upon successive extraction with ethyl acetate, gave a yield of (5: 1: 0.1, v/v). The results obtained after physiochemical analysis of the test drug showed 6.75 % Loss on drying at 1050C, 4.18% of Total Ash, 0.572% of Acid insoluble ash, 1.853% of Water soluble ash and more. The results obtained after preliminary phytochemical analysis showed the presence of Alkaloids, Carbohydrates, Glycosides, Phenols, Terpenoids, Tannins, and Saponins. The results indicate that the drug is of standard quality and may use as a reference standard in laying pharmacopoeia standards.