The plant Sesbania grandiflora (L).Pers or Agathi or Agasthya, belonging to family Fabeaceace, has great medicinal value in Indian traditional medicine for treatment of wide range of diseases that goes as a principal ingredient in preparation of Ayurveda medicinal formulations. It is used anthelmintic, diuretic, laxative, antigout antipruritus, antiepilepsy,skin disorders. The present study deals with the detail study of pharmacognostic, phytochemical and physiochemical investigation on fresh leaves and powder of Sesbania grandiflora L.