The worrisome rate at which antibiotic resistance is growing necessitates the development of alternative antimicrobial medicines. This in turn has motivated scientists to examine the antibacterial properties of several therapeutic herbs. One of these therapeutic plants is Lantana camara Linn, a large weed with a variety of medicinal benefits. There has been discovered to be effective in vitro antibacterial action against bacteria and fungi. Lantana camara also has larvicidal and anti-tumor properties, according to scientists. The known method was used in this study to examine the antibacterial effect of Lantana camara Linn in methanol and chloroform. Four distinct bacterium isolates, both Gram positive and Gram negative, were used to examine this activity. In order to create the crude extract, methanol and chloroform were used. Zones have detected antibacterial activity.