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ISSN 2063-5346
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Phytofabrication and characterization of silver nanoparticles and their enhanced antimicrobial activity

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Preeti Sharma1 , Basudha Sharma*2 , Indrakant Singh3 , Pratibha Kumari4
ยป doi: 10.31838/ecb/2023.12.11.11

Abstract

The application of plant phytometabolites in comparison to other biological approaches to nanoparticle bioreduction has piqued the interest of researchers.This paper reports the phytofabrication of silver nanoparticles.Fresh leaf extracts of Acokanthera oppositifolia and Leucaena leucocephala were utilized for the reduction and capping of silver ions. The structural properties of nanoparticles were studied using scanning electron microscope (SEM), transmission electron microscopy (TEM), X-ray diffraction (XRD), energy dispersive analysis (EDAX), and Fourier transform infrared spectroscopy (FTIR). The finding reveals that highly crystalline spherical silver nanoparticles produced with an average size of 13.38 nm and 11.93 nm for Acokanthera oppositifolia and Leucaena leucocephala, The antibacterial activity of synthesized silver nanoparticles was tested against Bacillus cereus, Staphylococcus aureus, Enterobacter aerogenes and Pseudomonas aeroginosa. To determine the enhancement in antibacterial activity, the zone of inhibition of the prepared AgNPs was compared to the fresh aqueous extracts, and finding shows that nanoparticles possess more antibacterial activity. Further research is being carried out to find out their other prospective applications. So we conclude that Phytomolecule โ€“ coated nanoparticles synthesis was found to be a simple, time-saving, cost-effective, and eco-friendly ideal strategy with superior properties.

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