Volume - 13 | Issue-1
Volume - 13 | Issue-1
Volume - 13 | Issue-1
Volume - 13 | Issue-1
Volume - 13 | Issue-1
Pharmaceutical products require attention for the Muslim community in relation to their halal status. Therefore we need a method that is able to authenticate the halalness of pharmaceutical products, one of which is through the volatilomics and chemometric approaches. This study is a narrative review on the application of volatilomics and chemometrics for halal authentication of pharmaceutical products from 2013 to 2020. The study results show that volatile compounds in a sample are typical compounds that can be used for halal authentication in various products, including pharmaceutical products. Halal pharmaceutical products containing alcohol and its derivatives critical points, gelatin, and collagen will be able to be detected using this method. Volatilomics using GC-MS as an instrument is a selective and sensitive method for authenticating halal pharmaceutical products. The spectral results from MS will be interpreted and visualized using chemometrics to make it easier to understand. PCA, PLSDA, and cluster analysis are chemometrics methods that reduce and present data more simply. The volatilomics approach combined with chemometrics is a method that can be an alternative for authenticating halal pharmaceutical products.