The goal of this study is to find out how the fruit powder and extract of Terminallia chebula can efficiently treat overweight rats' obesity. Six groups, every with six rats, had been formed from the 36 male albino rats, every weighing 160±10g. Rats have been given a high-fat diet (20% sheep fat) to assist them increase weight. The study assessed lipid fractions which includes triglycerides (TG), total cholesterol (TC), high-density lipoprotein (HDL), low-density lipoprotein (LDL), very low-density lipoprotein (VLDL), and atherogenic index (AI), glucose levels, liver enzymes that is Alanine amino transferase (ALT), Aspartate amino transferase (AST), & alkaline phosphatase (ALP) as well as renal biomarkers (creatinine, uric acid, and urea). The result confirmed that, when rats fed Terminallia chebula fruit extract, the treated groups showed considerably reduced glucose levels, liver enzymes, and renal biomarkers. In addition, lowest lipid fractions, such as TC and TG, LDL, VLDL levels, and AI %, had been observed, and vice versa for HDL levels. As conclusion, overweight rats have been fed an extract of Terminallia chebula fruit at a level of 500 mg/kg, displayed improving lipid profiles, glucose, liver enzymes, and renal function ranges. As a result, the research advises using Terminallia chebula fruit in the recommended meal and drinks for decreasing body fat percentages