Volume - 13 | Issue-1
Volume - 13 | Issue-1
Volume - 13 | Issue-1
Volume - 13 | Issue-1
Volume - 13 | Issue-1
Organometallic drugs of Ca(II), Fe(III), Co(II), Ni(II), Cu(II), Zn(II), Ag(I), Cd(II), Hg(II) and Pb (II) with N-(4-aminophenyl)-2-hydroxybenzamide ligand have much potential as therapeutic and cytotoxic agents against Prostatic carcinoma cell line (PC-3). Specific examples involving the design of metal complexes as anticancer and antimicrobial agents are discussed. These complexes have been synthesized and characterized using transmission electron microscope (TEM), Scanning electron microscope with EDEX, (mass, IR, UV-VIS and ESR) spectroscopy, XRD, as well as magnetic moments, conductance, elemental and thermal analyses. Molar conductance in DMF solution indicates that, the complexes are non-electrolytes. The ESR spectra of solid Cu (II) complex (8) showed isotropic type indicating an octahedral geometry with covalent bond character. X-ray Diffraction Spectroscopy XRD has been done. The XRD reveal that cu(II) complex (6) , Zn (II) complex (11) and Ag (I) complex (12) these complexes have the average crystallite sizes of 27.1,22.6 and 7.11 nm respectively.