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ISSN 2063-5346
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Pre and post test clinical study to evaluate the combined effect of Snehapana followed by Virechana and Shamanushadhi in reducing FPG, OGTT, and HbA1c in Prediabetes

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Dr. Aishwariya J Babu1 , Dr. Malu S Vimal2, Dr. James Chacko3, Dr. Mahesh Kundagol4, Dr. Devipriya Soman5*
» doi: 10.48047/ecb/2023.12.10.061

Abstract

Background: Prediabetes is the pre diagnosis of Diabetes. The current conventional medical management of Prediabetes includes lifestyle modifications and certain diabetic medications like metformin. But a large population of Prediabetic patients turn out to be diabetic. Prediabetes has similarity with Kaphaja Pramēha, owing to its comparable aetiology and clinical features. Progression of Prediabetes to diabetes can be prevented with an early intervention as Kaphaja Pramēha, which has a good prognosis. Objectives: To assess the combined effect of Snēhapāna followed by Virēcana and Śamanauṣadhi in reducing FPG, OGTT and HbA1c levels in Prediabetes. Materials and Methods: After the approval from IEC, an open label single arm pre and post-test clinical study was carried out in 20 subjects with Prediabetes diagnosed on the basis of ADA diagnostic criteria for Prediabetes. FPG, OGTT and HbA1c were tested. They were given Snēhapāna with Mūrchita Sarṣapa Taila followed by Virēcana with ri r tā i Cūrṇa and Niśākatakā i Kaṣāya as Śamanauṣadhi. Results: This study was completed with 20 subjects. Clinical symptoms shown statistical significance with p-value <0.05. FPG, OGTT and HbA1c improved by 33.08%, 16.57% and 11.72% respectively and showed a statistical significance of p-value .0001. Throughout the study, no adverse events were reported. Conclusion: The present protocol was effective in reducing the subjective and objective parameters of Prediabetes. Further research can be carried to see long term result of this protocol.

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