The increase in the number of patients with cancer, a high level of disability of such patients and, as a result, significant socio-economic losses of society maintain an enduring interest in improving cancer assistance to the population. In particular, the relevance of the prevention of cancer, both primary and secondary, remains acute. Oncogynecological preventative examinations were performed on 7818 women. Patients ranged in age from 25 to 75 years old, with an average of 40 years. During preventive examinations, the anamnesis, the state of the reproductive system and their pathologies, the course of pregnancy, the onset of menstruation and the period of menopause, inflammatory and other pathologies of the cervix, uterine body and ovaries were carefully studied. In the article, the authors represent the organizational aspects of the secondary prevention of malignant neoplasms of reproductive organs in women of the Khorezm region and give the results of a preventive examination of oncogynecological patients