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ISSN 2063-5346
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PREPARATION, CHARACTERIZATION AND MEDICINAL APPLICATION OF CHITOSAN BASED BIOMATERIAL

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M. Charumathy, Nalini R Uthaman, R. Saravanan, Bharti Ghude Wadekar N. Bhuvana, Zoyeb Mohamed Zia
» doi: 10.48047/ecb/2023.12.si4.1608

Abstract

Wastes from the leather industry include chrome shavings, which are rich in type I collagen and can be removed using an alkaline hydrolysis process. Since the generated collagen (Co) has qualities similar to those of the skin's extracellular matrix, it can be employed to speed up the healing of wounds. The linear polysaccharide chitosan (Ch) isolated from shrimp shells has been shown to hasten the development of fibroblasts and increase early phase reactions related to wound and burn healing. Wound dressings containing collagen and chitosan, a muco-adhesive fiber-producing natural polymer that offers an appealing alternative to traditional sustained medication release systems, are in the works. However, silver nanoparticles (AgNp) generated from Hibiscus rosa-sinensis are utilized in conjunction with collagen and chitosan to create a wound dressing material. Moisture content, porosity measurement, water absorption, and mechanical properties were among the tests performed on the wound dressing materials (Co-Ch-AgNp). FTIR was used to examine the functional groups. SEM analysis of the surface morphology.

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