Surgical site infections (SSIs) are a significant complication following surgical procedures, leading to increased morbidity, mortality, and healthcare costs. This review article aims to provide an overview of the prevalence and management of SSIs in Saudi Arabia. A comprehensive search of electronic databases was conducted to identify relevant studies published in English from inception to [current year]. The review includes studies that reported the prevalence of SSIs in various surgical specialties, risk factors associated with SSIs, and strategies for prevention and management in the Saudi Arabian context. The findings highlight the burden of SSIs in Saudi Arabia, with varying rates across different surgical procedures and healthcare settings. Factors such as patient-related characteristics, surgical techniques, and hospital infrastructure contribute to the occurrence of SSIs in the country. Furthermore, challenges in the diagnosis and management of SSIs, including antimicrobial resistance patterns, are discussed. The review also explores current guidelines and practices for the prevention of SSIs in Saudi Arabia, emphasizing the importance of multidisciplinary approaches and quality improvement initiatives. Recommendations for future research directions and implementation strategies to reduce the burden of SSIs in the Saudi Arabian healthcare system are provided.