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ISSN 2063-5346
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Prevalence of genetic polymorphisms in CYP19A1, gene in patients with polycystic ovarian syndrome in comparison with control and correlation with insulin resistance in Peer Panjal range(J&K)

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Arindam Basu, Aneesa Fatima, Sanjay, Qazi Najeeb Ahmed, Sajid Ali
» doi: 10.31838/ecb/2023.12.1.067

Abstract

PCOS is a common problem in youngerly age group which has got a genetic connection with insulin resistance Objectives: To identify the gene responsible for PCOS. Materials and Methods: genetic study was conducted using PCR and RFLP methods, Clinical examinations were conducted to correlate the same with the insulin resistance Results: CYP19A1 gene is not responsible for PCOS however we have found Multiple features which connects the same as aimed. Conclusion: Insulin resistance features such as Acanthosis nigricans /IFG/IGT or diabetes mellitus occurred in a high proportion of PCOS cases which could be due to excess cortisol.

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