INTRODUCTION: White blood cells do play a significant role when there is any deterioration of the vascular wall in diabetes.Thus, the neutrophil-to-lymphocyte ratio (NLR) became widely investigated.3,16The neutrophils are strongly associated with ongoing or impending inflammation and lymphocytes reflect the pathway of a regulated immune response to the inflammation AIMS AND OBJECTIVES: 1.To assess the relationship between neutrophil lymphocyte ratio and various levels of glycemic control in Type 2 Diabetes Mellitus patients. 2. To compare the relationship between neutrophil lymphocyte ratio and HbA1C in patients with excellent control, poor control, and worst diabetes control. 3. To study the correlation between neutrophil lymphocyte ratio and complications due to diabetes.MATERIAL AND METHODS: This comparative prospective study was conducted at the L.N. Medical college & research center associated with J.K. Hospital Bhopal during period of one and half year from December 2019 to August 2021. Research study was approved by institutional ethical committee. RESULTS: This study was a cross sectional study carried out at a tertiary care center located at urban area. A total of two thousand patients with type 2 diabetes mellitus were screened for their eligibility to be recruited for the study. CONCLUSION: . Neutrophil lymphocyte ratio correlates positively with HbA1c and presence of complications