The acceptance of the COVID-19 vaccination has become a controversial subject. Some groups in several countries were against it because of its ineffectiveness. The lack of knowledge experienced by the community and the government's lack of vigilance in vaccination has led to widespread rejection of the COVID-19 vaccine. Due to the differences in groups’ responses to COVID-19, breastfeeding women were chosen as the primary subject. This is because they are associated with differences in their responses to COVID-19 vaccination. study aims to describe public perception and acceptance of COVID-19 vaccination, specifically for breastfeeding women. The authors employed a 2020-2022 database with electronic searches on PubMed and Google Scholar. The articles that met the criteria for inclusion were then compared to one another, discussed, and drawn a conclusion. Prior study highlighted that a lack of awareness causes the wrong public perception of COVID-19 vaccination programs. In this regard, the current study revealed that this false perception occurred due to the absence of proper communication from the authorities, including health personnel, convincing people regarding the effectiveness of the COVID-19 vaccine.