Heart failure is a major and growing public health problem that leads to considerable morbidity and mortality. It characterized by progressive debilitating symptoms that negatively impact physical, mental and socioeconomic dimensions of quality of life of patients. Poor health-related quality of life is associated with low treatment adherence, re-hospitalization and increased financial burden for the patients and healthcare system. Quality of life was introduced as an outcome measure as well as a prognostic variable as many patients prefer improvement in quality of life at the expense of prolonged survival. Identifying meaningful factors influencing quality of life is critical to develop effective interventions to improve prognosis. The aim of this paper is to review the evidence- based information about quality of life in chronic heart failure.