Background: Severe organ failure due to an uncontrolled immune response to infection is known as sepsis. One kind of sepsis is septic shock. Aim & objectives: Objective: to evaluate the characteristics of outcomes in cases of septic shock and sepsis brought to the Emergency Intensive Care Unit (EICU)at Zagazig University Hospitals. Additionally, we are interested in comparing the outcomes for cases with sepsis & septic shock in the critical care unit. Patients and methods: This prospective cohort study was done on 360 cases that were collected in 6-months period, aged 18 years old or more both sexes sepsis & septic shock cases in EICU at Zagazig University Hospitals. Our cases were separated into 3 groups rendering to the cause of admission; Group A involved 284 cases with non-sepsis non-septic shock indications, Group B involved 40 cases with sepsis & Group C involved 36 cases with septic shock. Results: matched to Group A, Groups B & C showed significant differences in age, gender, BMI, GCS, APACHE II score, SOFA score, PH, PaO2, PCO2, HCO3, serum lactate, hospitalisation length, mechanical ventilation, and death (p < 0.001). The kind of bacteria in sepsis and septic shock groups was similar. Conclusion: There is still a significant rate of sepsis & septic shock in ICU in low- and middle-income countries LMICs, and these conditions are often linked to worse outcomes for patients.