The Suzuki coupling reaction, which forms carbon-carbon bonds between aryl halides and compounds containing boron, is a well-known and often employed process. Palladium is the catalyst in this reaction. The goal of the current research is to broaden the understanding of the Suzuki coupling reaction, especially with regard to difficult substrates and asymmetric variations. The Suzuki coupling reaction can be included into multicomponent and cascade processes, which could facilitate the quick synthesis of a variety of chemical structures. We present a brief review of the main features of the Suzuki coupling reactions in this article.