Numerous reasons have stymied advancement in the fight against pancreatic cancer. One of them is the overwhelming majority of patients' inability to identify the condition early. The current study proposes a fresh strategy for quickening development. This includes a focus on post-acute and chronic pancreatitis, diabetes mellitus, and excess intra-pancreatic fat deposition, all of which have the same goal of impacting the tumor's macroenvironment and microenvironment in the pancreas, and not in other organs. The two entities have the potential to be used in future screening plans in an effort to find pancreatic cancer earlier.