This study has aimed to investigate the relationship between creativity, innovation and entrepreneurship among women business owners in Chennai. In this regard, the relationship of the dimensions of creativity and innovation (fluency, initiative, adaptability) accompanied by characteristics of entrepreneurship (hard working, inquisitiveness, vision, perseverance, optimization of resources, resilience, time management) with entrepreneurship were investigated. Convenience sampling was adopted for the study wherein 257 women entrepreneurs formed the respondents of the study. The study identified a positive relationship between creativity, innovation and entrepreneurship. Structural Equation Modelling was applied to prove the hypothesized model. Moreover, the results showed that nature of business showed more influence on creativity, innovation and entrepreneurship.