Concrete is a construction chemical compound composed primarily of water, aggregate, and cement. Often, added constituents and reinforcements are incorporated in the mixture to accomplish the wanted functional characteristics properties) of the completed material. At point when these fix-ups are mixed together, they frame a liquid mass that is formed into shape. After some time, the concrete structures a hard grid which ties whatever remains of the fixings together into a solid stone-like material with numerous uses . Concrete is a to a great degree adaptable building material in light of the fact that, it can be designed for compressive strengths running from M 10, to 140 MPa or higher and workability going from 0 mm slump to 150mm slump or more. Concrete with a compressive strength under 50 MPa is viewed as ordinary strength. The basic elements of concrete in both of these occurrences are the same. However, the conclusion is its nearly equivalent proportioning. The study aims to investigate the effect of replacing sand by stone dust as fine aggregate in M35 grade concrete using different mix design methods such as ACI, DOE, USBR, and BIS. The properties of concrete such as compressive strength, tensile strength, and flexural strength were evaluated at 7, 14, and 28 days of curing. The study found that the replacement of sand by stone dust as fine aggregate had a significant effect on the strength properties of M35 grade concrete. The results obtained were compared with the specifications provided by the respective mix design methods.