Nanotechnology has changed every industry because of its unique and obvious effects, which have helped scientists make many advances in the medical, agricultural, and other fields. Because they kill bacteria so well, The utilisation of AgNPs is observed in many commercial, household, and Pharmaceutical goods. Since the beginning of human society, silver and silver compounds have been used, Nevertheless, the production of Ag NPs has only lately been made public. In both horticulture and health, they have been used especially as antimicrobials, antifungals, and vitamins. The fact that multidrug-resistant microbes cannot be successfully managed by existing treatments makes them a pressing global concern. Consequently, it is imperative to new antibacterial drugs. Silver nanoparticles (Ag-NPs) are a potential solution of antibacterial substances. It has been demonstrated that by combining Ag/Ag+ with the proteins already present in the microbe cells, Ag NPs prevent many bacteria and fungi from developing and reproducing. Ag NPs have the potential to produce free radicals and reactive oxygen species, which, by obstructing cell reproduction, promote apoptosis and cell death. The SEM as well as TEM photographs of the mixture comprising of pathogens and nanoparticles indicate that the tiny size of Ag-NPs in comparison to microbes enables them to infiltrate cells and result in damage to the cell wall. A lot of research has been done on how metal nanoparticles are made by actinomycetes and how they kill bacteria. Not much attention has been paid to making metal nanoparticles from secondary compounds and new molecules made by actinomycetes. The main focus of the current research is the biosynthesis of metal nanoparticles as well as the possibility of studying compounds made by microorganisms. This study also talks about how to make biogenic metal nanoparticles, keep them from being toxic, and use their unique interactions with biological systems to make them more effective as therapeutic agents in the pharmaceutical and medical industries.