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ISSN 2063-5346
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"REVOLUTIONIZING TABLET ANALYSIS: CONCURRENT SPECTROPHOTOMETRIC QUANTIFICATION OF BENAZEPRIL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE"

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Dr. Shailesh B. Patil, Prof. Jitendra D. More
» doi: 10.53555/ecb/2022.11.6.35

Abstract

A novel analytical technique has been advanced for the concurrent valuation of Hydrochlorothiazide (HCT), and benazepril HCl (BEN) in tablet formulation. This technique, based on the concurrent equation approach, offers simplicity, accuracy, precision, reproducibility, and cost-effectiveness. Utilizing methanol as the solvent and measuring at 240.0 nm and 270.0 nm, the method demonstrates linearity for BEN and HCT in the conc. ranges of 04–14.0 µg/mL, and 02–12.0 µg/mL, respectively, corresponding to their respective ????max. The recovery studies validate the accurateness of the concurrent equation method, with BEN exhibiting recoveries between 100.1% to 100.5% and HCT between 100.0% to 100.1%. This method is recommended for routine analysis due to its speed, simplicity, accuracy, sensitivity, and specificity, making it suitable for practical applications.

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