Otosclerosis is a complex and progressive disease of bone of otic capsule.1 Mature lamellar bone is replaced by osteoblasts with the bone of more thickness, cellularity, and vascularity.2 It mainly affects the stapes footplate especially the fissula ante fenestram and can extend to the inner ear causing cochlear otosclerosis, which can be termed as mixed otosclerosis. With an incidence of 1–2% of the white population, otosclerosis is among the most common causes of acquired hearing impairment. Aim: in this study; we reviewed the Bone Cement Application in Patients with Otosclerosis, Summary: The use of hydroxyapatite bone cement in primary stapedotomy may have a role in providing stability for the procedure decreasing the incidence of recurrent conductive hearing loss in otosclerosis patients. This can provide a substitute for the problems of malcrimping of the prosthesis