This review article explores the crucial role of nurses and other healthcare workers in implementing strategies to enhance healthcare access and equity for marginalized populations. As disparities in healthcare access and outcomes persist among vulnerable groups, such as low-income individuals, racial and ethnic minorities, and individuals with disabilities, it is imperative to address these inequities through targeted interventions. Nurses and other healthcare professionals play a vital role in bridging the gap in healthcare access for marginalized populations by providing culturally competent care, advocating for policy changes, and promoting health education and prevention programs. This article synthesizes current literature on the subject and highlights effective strategies employed by healthcare workers to address healthcare disparities among marginalized populations. By understanding the unique challenges faced by these populations and implementing evidence-based interventions, nurses and healthcare workers can contribute significantly to improving healthcare access and equity for all individuals.