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ISSN 2063-5346
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ROLE OF PHASE TRANSFER CATALYST IN SYNTHETIC ORGANIC CHEMISTRY

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Shallu Devi, Navneet Kaur, Rajeev Sharma, Manvinder Kaur, Harvinder Singh Sohal
» doi: 10.53555/ecb/2023.12.12.276

Abstract

Phase-transfer catalysis (PTC), a common technique for generating organic compounds, has been around for more than three decades. Reactions involving reagents in two immiscible phases are made possible by phase transfer catalysis (PTC), which uses catalytic doses of phase transfer agents to facilitate species inter-phase transfer. PTC is commonly used in the liquid-liquid and solid-liquid creation of a variety of chemical substances. Understanding numerous researches have focused on the breadth and operation of PTC. Incorporating a Phase transfer catalyst is more efficient when combined with other rate-increasing methods including ovens, electro-organic synthesis, and the process of photochemistry a topic of increasing investigation. Organic intermediates and fine chemicals can be created by using these applications; molecules appear to have almost no boundaries. PTC can be employed in several organic processes, such as Michael addition, aldol condensation, and nucleophilic substitution. Since it can aid in the solubilization of ionic species in non-polar solvents, it is especially helpful in processes involving ionic species. PTC is an effective instrument for transferring reactants between phases quickly and effectively, which promotes the reaction at the interface between them. In many cases, it is used as an intermediate in the synthesis of many different chemical molecules and has developed into a significant technology in both academia and industry

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