Our sages described three vital organs and Shiras is one among them. They highlighted the importance of the head, i.e., Shiras, because the vital organs are necessary for the survival of the body. Shiras is the seat of all Gyanendriyas and controls the functions of Karmendriyas. Acharya Charaka has defined that Shira (head) as Uttamanga. The term Shiroroga has been used to describe the painful condition of head. All the Samhitas describe Ardhavbhedaka while explaining Shirorogas. The term Ardhavabhedaka is composed of two parts: Ardha and Avabhedaka. Thus, the literal meaning of Ardhavabhedaka is a piercing or bursting out type of pain in one half of the head. Yoga a well known scientific method of living a healthy life at all planes i.e. spiritual, emotional and physical, levels. Mudra Vighyan is one of the important chapters in Yoga, which is being used to attain health and spiritual awakening by maintaining the balance of Panchmahabhoot and trigunas. Prana Mudra is formed by the combination of ring finger and little finger with thumb, which in result balances Apaya Mahabhoot and Prithivi Mahabhoot and enhances the Prana Tattva of the body. As the Shira (head) is Pranayatana and Adhisthana of all Indriyas, thus by practicing Prana Mudra, the Prana tattva will enhance and Tridosas balance can be achieved which led to management of Ardhavbhedaka.