Public health nurses are essential frontline healthcare professionals who play a critical role in disaster preparedness and response efforts. Their expertise and skills are invaluable in providing emergency care and support to communities during times of crisis. This study delves into the specific roles and responsibilities undertaken by public health nurses in disaster preparedness and response, shedding light on the challenges they encounter while fulfilling these crucial duties. During disaster response, public health nurses are at the forefront of providing immediate medical care, conducting assessments of community health needs, and coordinating with other healthcare providers to ensure a coordinated response. They may set up temporary clinics, distribute essential supplies, and provide psychological support to individuals affected by the disaster. Public health nurses also play a crucial role in monitoring for potential outbreaks of infectious diseases, ensuring the safety of food and water supplies, and addressing the mental health needs of disaster survivors. Despite their vital contributions, public health nurses face various challenges in fulfilling their roles during disasters. These challenges may include limited resources, inadequate training in disaster response, communication barriers, and high levels of stress and burnout. Additionally, the unique nature of each disaster presents unpredictable circumstances that require adaptability and quick decision-making on the part of public health nurses. By gaining a deeper understanding of the specific contributions of public health nurses in disaster situations, policymakers and healthcare organizations can better support and utilize these essential healthcare professionals in times of need. Investing in training programs, resources, and infrastructure to enhance the capabilities of public health nurses can improve overall disaster preparedness and response efforts, ultimately leading to better outcomes for communities facing emergencies.