To investigate the impact of Vitamin C therapy on individuals with burns. Methodology: The research conducted at the Hospital of Surgery and Burns, Dhule, from January 2020 to October 2021 included 20 adult patients with severe burns (over 30%). Individuals with pre-existing disorders and co-morbid conditions were excluded from the study. Outcomes: For patients in Group A, the calculated fluid requirement was 3.74 ± 0.57 ml/kg/% of burns, whereas for patients in Group B, it was determined to be 2.46 ± 0.54 ml/kg/% of burns. In terms of urine output, Group A had an average of 1.05 ± 0.28 ml/kg/h, while Group B exhibited a higher urine output of 1.42 ± 0.39 ml/kg/h. Importantly, Group B showed reduced fluid retention and body weight increase compared to Group A. Conclusions: When high-dose Vitamin C (12-15 grams) is administered as an adjuvant treatment during the first 48 hours of resuscitating burn cases, it has been found to decrease fluid requirement, increase urine production, and reduce fluid retention in the body