A straightforward, accurate, and long-lasting reverse phase RP-HPLC has been verified for the simultaneous quantification of remogliflozin and teneligliptin in API and pharmaceutical dosage form. This method makes use of an Aglient column, Aglient HPLC chromatographic separation, and PDA detection along with a straightforward isocratic mobile phase made up of Acetonitrile: KH2 taken in the ratio (35:65). Remogliflozin and teneligliptin's average retention times were discovered to be 2.263 min. and 2.994 min. respectively, indicating the approach can be employed for the regular testing. Remogliflozin and teneligliptin's linearity was found to be linear with a r2 of 0.999 for all drugs, suggesting that the method can produce acceptable responsiveness. The RSD should not be greater than 2.0% according to the precision acceptance. Remogliflozin & teneligliptin were found to have % RSDs of 0.5 and 0.6, respectively, demonstrating the accuracy of the approach