A novel strategy for the quinoxalines derivatives have been developed by condensation of 1,2-diaminoarenes with 1,2-diketones or 2-bromo-1-arylethanone in presence of TBAF as the catalyst. This strategy seems to suitable for the construction of numerous 2-phenylquinoxalines, biquinoxalinephenazine, and tetraphenyl-biquinoxaline analogue with high productivity. This protocol allows C-N bond formation with excellent scope and highly substituted group tolerance under mild and ease condition. The mild reaction condition, easy purification process and high reaction rate afford excellent yields it makes this methodology an ideal alternative substitute for the conventional acid/base or metal catalyzed thermal processes.