One of the main causes of diarrhea in India is shigellosis. Although shigellosis is common in the nation and has been implicated in numerous outbreaks, exact estimates of morbidity and mortality attributable to the disease are scarce. According to the scant information available, shigella is a significant food-borne disease in India.The most prevalent species is Shigellaflexneri, although non-agglutinableshigellae and S. sonnei are rapidly emerging and S. dysenteriae has temporarily vanished from the northern and eastern regions. There have been numerous global outbreaks of shigella strains that are resistant to antibiotics. The global spread of multidrug resistant Shigella, particularly the rise in resitance to azithromycin, third-generation cephalosporins, and fluoroquinolones, is particularly significant. Shigellosis prevention is preferred since it will significantly lower the morbidity related to diarrhea in the nation. To lessen the burden of shigellosis, public health interventions like providing clean water and proper sanitation are crucial. However, India's resource shortage is a complicated problem that will take some time to overcome. Therefore, the scientific effort should concentrate on creating a multivalent vaccine that is both safe and inexpensive. The epidemiology, disease burden, and therapeutic difficulties of shigellosis from an Indian viewpoint are the main topics of this paper.Foodborne diseases related to unhygienic food handling practices remain a major public health problem across the globe.