Phytomedicines are increasingly a crucial component of improving healthcare and have promising futures in many nations. The herbaceous medicinal weed Heliotropium indicum Linn. also referred to as "Indian heliotrope" (Hathishur), is a member of the "Boraginaceae" family and is very common in India. It has a long history of traditional medicinal uses in many different nations around the world. Along with India, Bangladesh, and a few other African nations, these therapeutic herbs can be found worldwide in both tropical and temperate regions. Therefore, in the current work, the hydroalcoholic (Polar) and n-hexane (Non-Polar) extracts of Heliotropium indicum Linn were analyzed using high-performance thin-layer chromatography (HPTLC) to determine their phytochemical profiles.